Research Projects

Rapid Time-Resolved 3D Phase-Contrast Pediatric Cardiovascular MRI


Michael Lustig, Shreyas Vasanawala1 and Martin Uecker

Magnetic resonance imaging provides essential information used in the care of children with heart defects: heart function (chamber sizes and pumping efficiencies), blood flow (in various vessels and across heart valves), and anatomy. However, as MRI exams take longer than an hour and require children to remain motionless, anesthesia is often required, which is risky in these fragile patients. This project will develop and validate a rapid comprehensive MRI technique for evaluation of congenital heart defects. In particular we aim to develop velocity encoding strategies with high velocity-to-noise ratio and large velocity dynamic range, subsampling strategies for 3D time resolved phase-contrast, Reconstructions from subsampled data that exploit spatio-temporal sparsity of 4D flow, fast and clinically feasible implementation and clinical validation.


1Stanford University