In recent years, high throughput biological techniques have been developed to collect data on the genomic response of an organism to stress. We employ DNA microarray technology to gain a survival snapshot of haploinsufficient Saccharomyces cerevisiae (bakers' yeast) in the presence of several antifungal drugs, anticancer drugs, and environmental stresses. Using well-known statistical and machine learning techniques, we identify protein targets and side effects of these stresses with a measure of confidence. This information is further used to hypothesize previously unknown protein functions, molecular and genetic pathways, and drug interactions.