EECS Department Colloquium Series
Precision Medicine at UC San Francisco
Wednesday, September 25, 2013
Keith R. Yamamoto
Precision medicine is a concept that would aggregate, integrate and analyze all information about biological events and processes, drawing on vast collections of data to produce accurate health advice and predictions, and disease diagnoses, tailored to the individual. Precision medicine will be enabled by creation of a vast computational information commons, within which a continuously growing set of correlations produce a knowledge network, generating new fundamental hypotheses, illuminating mechanisms of disease, and establishing mechanistic links between diseases thought to be unrelated. The potential to tailor prevention, diagnosis and treatment precisely to individuals will revolutionize development and deployment of therapies, as well as principles of clinical practice, by allowing all stakeholders to both benefit from and participate in the research, health and healthcare enterprise.
Dr. Keith Yamamoto obtained his PhD from Princeton University. He is currently vice chancellor for research, executive vice dean of the school of medicine, and professor of cellular and molecular pharmacology at the University of California, San Francisco. Throughout his career, Dr. Yamamoto.s research has focused on signaling and transcriptional regulation by nuclear receptors; he uses structural, mechanistic and systems approaches to pursue these problems in pure molecules, cells and whole organisms. Dr. Yamamoto has led or served on numerous national committees focused on public and scientific policy, public understanding and support of biological research, and science education; he chairs the Coalition for the Life Sciences, and he serves on the Advisory Committee for Division of Earth and Life Studies for the National Academy of Sciences, following six years as chair of the Board on Life Sciences within that division. Dr. Yamamoto has chaired or served on many committees that oversee the process of peer review and the policies that govern it at the National Institutes of Health; currently, he sits on the Advisory Council of the NIH Center for Scientific Review. He chairs the External Advisory Committee for the Watson School of Biological Sciences at the Cold Spring Harbor Laboratory, serves as a member of the advisory boards for Research! America, the Lawrence Berkeley National Laboratory and Burrill & Company, and sits on the Council of the Institute of Medicine. Dr. Yamamoto is an elected member of the National Academy of Sciences, the Institute of Medicine, the American Academy of Arts and Sciences, and the American Academy of Microbiology, and is a fellow of the American Association for the Advancement of Science.
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